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ProCal manages calibration. Seal can stop a step if its instrument is not eligible.

Seal, the GxP execution system, is your eBR, your QMS and more. Neil, your AI agent, does the paperwork across your systems. You sign. Paradromics cut operator paperwork by 80%. Start with one process beside ProCal.

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Where ProCal falls short.

From TMA Systems’ own pages.

  • TMA calls it
    “pre-validated”
    Its team, per a customer
    “design, configuration, training and validation”
    Seal
    Neil, then your approval

    Configured with the vendor’s team.

    TMA calls ProCal “pre-validated”, yet a customer on the same page credits the vendor’s team with “design, configuration, training and validation of the solution”. In Seal, Neil configures the first process from your procedure, and your team approves it.

    TMA Systems, ProCal
  • 1989
    Calibration software
    2023
    Bought by TMA Systems
    Lab, batch and quality
    Not among TMA’s products

    A calibration system, on its own.

    Prime’s calibration software dates from 1989, and TMA Systems, a facilities maintenance software vendor, bought Prime in 2023. TMA lists no LIMS, batch records or quality system. In Seal, the lab, the batch and quality are one set of records.

    TMA Systems, About
  • A failed calibration
    Flagged immediately
    Then
    An audit-ready report
    The batches it measured
    In other systems
    Seal
    Traced through recorded uses

    A failure is flagged and reported.

    ProCal flags a failed calibration immediately and generates audit-ready reports. In Seal, a failed point is traced through recorded uses to the batches and tests the instrument measured.

    TMA Systems, ProCal
  • A past-due tool
    Paused
    After passing
    Restored
    Seal
    Separate decisions

    A pass puts it back in service.

    TMA says its software can pause past-due tools and restore them after passing. In Seal, the passing result, the permission to use and the assessment of earlier work are separate decisions.

    TMA Systems, Calibration management software

See it in Seal.

Real Seal screens with fictional test data: a calibration out of tolerance, the earlier work it touched, and a repair.

  1. 1

    A calibration keeps its first reading.

    CAL-0882 records the original error beside the adjusted one, restricts the instrument’s use, and opens a review of its earlier work.

    Calibration CAL-0882 of shelf-temperature probe TT-204 in Seal: five reference points with original and final errors, the −40 °C point originally outside limits, the adjustment, use restricted while review stays open, and the linked prior-use assessment OOT-061.
    1. The original error, kept−0.8 °C at −40 °C stays recorded beside the final −0.1 °C.
    2. Use restrictedNot authorised until review and earlier use are settled.
    3. Earlier use, assessedOOT-061 follows the instrument into its earlier work.
  2. 2

    The instrument, followed into its work.

    OOT-061 finds each batch and qualification the instrument measured in the review window.

    Assessment OOT-061 in Seal: the calibration event and original point, a review window from 3 February to 7 September 2026, the recorded uses in two freeze-dryer batches and a temperature mapping, each open, and the evidence needed before a decision.
    1. The review window3 February to 7 September 2026; when the error began is unknown.
    2. Every recorded useTwo freeze-dryer batches and a temperature mapping, each open.
    3. Evidence before a decisionSource traces and independent probes, compared first.
  3. 3

    Maintenance on the same records.

    WO-007 starts from the calibration finding, records the repair, and checks the pump before it returns to use.

    Work order WO-007 in Seal to investigate low pump flow on HPLC-007: the source calibration finding and maintenance plan, the repair with part lot and technician, three post-service flow readings against 0.98 to 1.02 mL/min awaiting review, and the return-to-service review.
    1. From the calibration findingCAL-007: pump flow outside tolerance.
    2. The repair, recordedThe part, its lot and the technician.
    3. Checked before returnThree flow readings against 0.98 to 1.02 mL/min.

What Seal’s customers measured.

Each figure links to the customer’s story.

QualityAcclinate and Skye Biologics

−50%
quality cycle times at Acclinate, from a procedure change to everyone trained.Acclinate
−40%
non-conformances at Skye Biologics, with training checked before execution.Skye Biologics

RecordsMiAlgae and Bioventix

−75%
documentation time at MiAlgae, from the lab to commercial production.MiAlgae
−80%
document admin time at Bioventix, after two decades on paper.Bioventix

ProCal and Seal, side by side.

Every source is listed under References.

ProCalSeal
What it isCalibration management software¹The GxP execution system, with calibration built in
Data modelThe calibration schedule, record and certificate¹Primitives your team composes: record types, their relationships, steps and checks
CoversCalibration management; one customer also tracks PMs and work orders¹Calibration, development, lab, manufacturing, quality
Configuring itUser-defined fields, custom approval workflows¹Neil, Seal’s AI agent, prepares it from your procedures; your team approves
Test executionGuided routines, automated maths¹Every calibration point kept with its source and standard
A failed calibrationFlagged, with audit-ready reports¹Traced through recorded uses to batches and tests
After a passing checkPast-due tools restored on passing²Use decided for the range in use
CertificatesGenerated automatically¹Reconciled against the instrument
Getting startedA project with the vendor’s team¹A 48-hour evaluation of one process, once the scope is agreed and the inputs received

Summary

The story
ProCal is good for calibration management. It comes from Prime Technologies, whose calibration software has been sold since 1989, and TMA Systems, a maintenance software vendor, bought the company in 2023.³⁴ Its model is still the calibration schedule, record and certificate for each instrument, loop and piece of equipment.¹ TMA calls it “the only pre-validated, 21 CFR Part 11–compliant calibration program”, yet the customer quoted on the same page credits the vendor’s team with supporting its own in “design, configuration, training and validation of the solution”.¹ If calibration is a job of its own, it can work well. Most teams need a failed calibration traced to the results and batches it affects, and eligibility checked at the moment of use, in the same system as the work.

1What ProCal offers.

ProCal is calibration management software from Prime Technologies, whose calibration software dates from 1989, and which TMA Systems acquired in January 2023.³ It schedules calibrations with reminders, runs pre-engineered test routines, applies tolerances with automated calculations, flags pass or fail and generates certificates, with audit trails, electronic signatures and approvals.¹ Technicians capture as-found and as-left readings online or offline.²

2Running Seal alongside ProCal.

Teams move instruments to Seal one at a time, with ProCal connected while they do. Seal’s ProCal connection brings ProCal calibration records into equipment checks and investigations in Seal. ProCal provides a Data Exchange Utility and ProCal Connector, and Seal scopes the connection around your installed edition, licensed tools and available exports. It is a custom integration, not a guided Seal connector, and it does not assume a REST API or automatic access to every calibration record.

Agree the instrument identifiers, calibration fields, transfer frequency and source timestamps before mapping records into Seal. Confirm which dates, results, approval states and certificate references the transfer includes. Start with reading evidence; changes to ProCal need separate configuration. Missing or stale evidence stays visible in the receiving equipment check.

Once the connection and equipment mappings are configured, Neil can:

  • compare the supplied calibration due date with a planned run and flag gaps for the equipment owner;
  • trace an instrument with an out-of-tolerance result to its recorded uses in Seal and prepare the batch list and evidence for quality review;
  • collect overdue items and unresolved evidence into a work list for the metrology team.

3Moving from ProCal to Seal.

Start with one critical instrument and prove the whole chain, so nothing has to move on day one.

  1. Choose a critical instrument, ideally one with several ranges and uses that matter, such as a freeze-dryer shelf-temperature transmitter.
  2. Bring its master data, criticality, procedure, reference standards and a recent calibration with its certificate. Start with sample material, or arrange an NDA before sharing confidential records.
  3. Neil drafts the instrument, reference-standard and calibration-point templates, capture fields for the original and post-adjustment datasets, and versioned calculations and decision rules. Metrology specialists review the model. Once the scope is agreed and the inputs received, Seal prepares the first working process and its validation pack to evaluate within 48 hours. Production timing then depends on scope, interfaces, migration and your release requirements.
  4. Connect ProCal for the dates, results and certificate references the process needs.
  5. Take the instrument through an as-found failure, adjustment, as-left pass, restriction, use-history extraction and interval review. Include an overdue standard, an external certificate mismatch and an interface outage.
  6. Agree which system owns instrument identity, schedules, results and current restrictions before extending to the next instrument family.

Retention obligations continue for the records that stay in ProCal. The calibration blueprint describes the workflow in detail.

References

  1. 1ProCal calibration management software, TMA Systems. https://www.tmasystems.com/products/procal (read 5 November 2026)
  2. 2Calibration management software, TMA Systems. https://tmasystems.com/solutions/calibration-management-software (read 5 November 2026)
  3. 3TMA Systems Acquires Prime Technologies, TMA Systems, 11 January 2023. https://www.tmasystems.com/press/tma-systems-acquires-prime-technologies (read 5 November 2026)
  4. 4About TMA Systems, TMA Systems. https://www.tmasystems.com/about (read 5 November 2026)

AQuestions and answers

Is Seal better than ProCal?

Yes. ProCal is good for calibration management. It comes from Prime Technologies, whose calibration software has been sold since 1989, and TMA Systems, a maintenance software vendor, bought the company in 2023. Its model is still the calibration schedule, record and certificate for each instrument, loop and piece of equipment. TMA calls it “the only pre-validated, 21 CFR Part 11–compliant calibration program”, yet the customer quoted on the same page credits the vendor’s team with supporting its own in “design, configuration, training and validation of the solution”. If calibration is a job of its own, it can work well. Most teams need a failed calibration traced to the results and batches it affects, and eligibility checked at the moment of use, in the same system as the work. Seal has no fixed model of one kind of work. It is built from primitives: record types, the relationships between them, and the steps and checks that use them, which your own team composes into your process, with Neil able to prepare each change for approval. So one platform runs process development, the laboratory, manufacturing, batch release and the quality system, and each change becomes a new version, released once its selected tests pass, while earlier runs keep theirs. Moving from paper and legacy systems, Paradromics keeps calibration records on one platform and cut operator paperwork by 80%.

Is Seal an alternative to ProCal?

Yes. ProCal is designed for calibration management. Seal covers calibration management, from each point with its standard and procedure to use permission and certificate review, and keeps it on the same records as maintenance, laboratory, manufacturing and quality. An out-of-tolerance point in Seal leads straight to the batches and tests the instrument measured since its last acceptable check.

Is Seal a calibration management system?

Yes. Seal keeps each calibration point with its as-found and as-left values, times, recorder, procedure and reference standard, reconciles vendor certificates against the instrument and the ordered scope, and decides use permission for the range at use. Procedure and interval changes are released with their verification.

Can Seal connect to ProCal?

Yes, as a scoped custom integration. ProCal provides a Data Exchange Utility and ProCal Connector, and Seal confirms the edition, licensed tools, fields and transfer frequency with your team before mapping records. It starts with reading evidence, so Seal can check due dates before a run and Neil can trace an out-of-tolerance instrument to its recorded uses.

Does Seal keep as-found results after adjustment?

Yes. As-found data are recorded in full before any adjustment or repair, and as-left testing records the final condition as a separate dataset. A passing as-left result cannot replace or hide a failing as-found condition.

How long does it take to start with Seal?

Once the scope is agreed and the inputs received, Seal prepares a first working process and its validation pack to evaluate within 48 hours, configured from one of your procedures. Production timing then depends on scope, interfaces, migration and your release requirements.

Start beside ProCal.

Start with one critical instrument. Seal’s ProCal connection reads calibration evidence through ProCal’s Data Exchange Utility or ProCal Connector, so nothing has to move on day one.

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