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GxP that learns.

Neil is the AI brain for all your GxP work.Configure and run lab, manufacturing and quality workflows on Seal.

Illustrative CAR-T release. Eight runs of version 4 of a procedure in Seal, post-thaw viability drifting down toward its 90% specification and reaching 91.4%. Neil drafts a reduction in the post-thaw hold from 45 to 30 minutes. The process owner reviews and approves version 5, whose runs hold around 96%.

50+ companies, from GxP labs to GMP manufacturing.

Hand Neil the paperwork. Keep the decisions.

Ask why viability is falling. Neil reads the records and drafts the investigation, sources attached.

An illustrative job for Neil
Investigations › QA-PROC-014 › Post-thaw viability
drafted by Neil

Why is post-thaw viability falling?

Longer holds coincide with lower viability. All eight runs stayed within the approved limit.

Post-thaw viability94.6% → 91.4%
Run 210Specification: ≥ 90%Run 217

Investigate the hold. Review a shorter limit.
3 sources attached for review

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Validated, not frozen.

Most validated systems freeze. Here Neil proposes a change, its tests run, and your team releases it.

Changesets › QA-PROC-014 › Changeset #14
in review
CAR-T release
v04 → v05

Step 03 · Post-thaw hold

  • Hold timeLimit 45 30 min, thaw to count
  • +Over the limitOpens a deviation, stops the step

Proposed by Neil from evidence across 8 runs.

Tests

12 of 12 passed on v05

QA approval

Awaiting signature

See how continuous validation works

From SOP to running system in weeks.

Give Neil an SOP, batch record or form. It configures the steps, fields and checks your team runs.

Batches › CAR-T › B-2214
in progressv01
CAR-T manufacturing
Patient COI-2214
  1. 1Apheresis
  2. 2Selection
  3. 3Activation
  4. 4Transduction
  5. 5Expansion
  6. 6Harvest
  7. 7Formulation
  8. 8Cryopreservation

Step 4 of 8 · SOP-MFG-021 §6.4

Transduction

Add vector at an MOI of 4 to 6 within 2 hours of activation.

Vector lotLV-118Released
BioreactorProdigy-3Qualified
Viable cells1.2 × 10⁸≥ 1.0 × 10⁸
MOI5.0Target 4 to 6
Since activation1 h 40 minWithin 2 h
OperatorOP-0917Trained on v01
Sign stepSecond-person check next
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Seal links every batch, sample and procedure, so Neil can answer an auditor in minutes.

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Questions about Seal.

What is Seal?

Seal is the GxP operating system for biopharma. Configure and run lab, manufacturing and quality workflows, then evolve them with Neil, your AI agent.

Why Seal over a standalone LIMS, QMS or MES?

Lab, manufacturing and quality run on one platform, so a result, its batch and its investigation are linked rather than reconciled across systems, and Neil can work across all of them. Start with one workflow and add the next when you are ready.

How are changes validated?

Each change carries its specifications, test evidence and required approvals, so a validated process can keep improving instead of freezing. Your team verifies each change before release, and earlier runs keep the version they used.

Can Neil change a live process?

Neil proposes changes. Your team tests and approves them before they go live. Neil works within your permissions; you can disable AI across the organisation.

Do we have to replace our existing systems?

No. Start with one process, connect the systems you keep and move more work into Seal when you’re ready.

Who uses Seal?

Paradromics, Bioventix, Acclinate, Skye Biologics and MiAlgae. Read their customer stories for measured results.

See your process in Seal.

Bring an SOP, a batch record or a problem that keeps coming back. See Neil configure it.

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