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AI that improves every GxP run.

Seal is the platform your lab, manufacturing and quality work runs on.Neil is the AI agent that improves how it runs, with Seal or without.

Illustrative CAR-T release. Eight runs of version 4 of a procedure in Seal, post-thaw viability drifting down toward its 90% specification and reaching 91.4%. Neil drafts a reduction in the post-thaw hold from 45 to 30 minutes. The process owner reviews and approves version 5, whose runs hold around 96%.

50+ companies, from GxP labs to GMP manufacturing.

Seal runs the work. Neil does the legwork.

Two products, made to work together. Neil reads every system you have.

SealThe GxP platform

Seal › Batch records
B-2407T-24 tablets, 100 mg
Execution
Complete
Batch records
Dispensing
18 weights from the scale
MES
Press
TP-02, calibrated
Equipment
Lactose
Lot L-5521, released
Inventory
Deviation
DEV-038, open
QMS
Review plan
BR-012 v06
Documents
Operators
4, all trained
Training
Process
From development run R-118
ELN
QC reports
Assay, 1 of 3
LIMS
Stability
On study ST-12
Stability
Explore the platform

NeilThe AI agent

Neil › Jobs
Neil working
Prepare B-2407 for review
Read
B-2407 from every system
Seal, SAP, AVEVA PI, Outlook
Learned
How you review a batch
Skill v3, approved by QA
Flagged
2 QC reports missing
DEV-038 not assessed
Predicted
Hardness at limit by B-2413
TP-02's force, from AVEVA PI
Proposed
Add hardness trend to BR-012
A change for QA to approve
Drafted
Review brief
3 findings, sources linked

NextQA reviews the draft and decides.

Meet Neil

Hand Neil the paperwork. Keep the decisions.

Ask why viability is falling. Neil reads the records and drafts the investigation, sources attached.

An illustrative job for Neil
Investigations › QA-PROC-014 › Post-thaw viability
drafted by Neil

Why is post-thaw viability falling?

Longer holds coincide with lower viability. All eight runs stayed within the approved limit.

Post-thaw viability94.6% → 91.4%
Run 210Run 217

Investigate the hold. Review a shorter limit.
3 sources attached for review

Explore 179 integrations

Validated, not frozen.

Most validated systems freeze. Here Neil proposes a change, its tests run, and your team releases it.

Changesets › QA-PROC-014 › Changeset #14
in review
CAR-T release
v04 → v05

Step 03 · Post-thaw hold

  • Hold timeLimit 45 30 min, thaw to count
  • Over the limitOpens a deviation for QA

Proposed by Neil from evidence across 8 runs.

Tests

12 of 12 passed on v05

QA approval

Awaiting signature

See how continuous validation works

From SOP to running system in weeks.

Give Neil an SOP, batch record or form. It configures the steps, fields and checks your team runs.

Batches › CAR-T › B-2214
in progressv01
CAR-T manufacturing
Patient COI-2214
  1. 1Apheresis
  2. 2Selection
  3. 3Activation
  4. 4Transduction
  5. 5Expansion
  6. 6Harvest
  7. 7Formulation
  8. 8Cryopreservation

Step 4 of 8 · SOP-MFG-021 §6.4

Transduction

Add vector at an MOI of 4 to 6 within 2 hours of activation.

Vector lotLV-118Released
BioreactorProdigy-3Qualified
Viable cells1.2 × 10⁸≥ 1.0 × 10⁸
MOI5.0Target 4 to 6
Since activation1 h 40 minWithin 2 h
Vector volume2.4 mLMatches MOI
Sign stepTrained on v01Second-person check next
Explore the platform

One platform for every GxP system.

Seal links every batch, sample and procedure, so Neil can answer an auditor in minutes.

See all 122 GxP blueprints

Ready for your quality and IT review.

  • SOC 2 Type 2

    Security controls audited by an independent firm.

  • 21 CFR Part 11 and EU GMP Annex 11

    Audit history and electronic signatures kept with every record, qualified for your intended use.

  • GAMP 5, Second Edition

    Requirements, verification and change control are part of how every process changes.

  • Your data stays yours

    Under Seal’s agreements, your data is not used to train the underlying AI models.

Trust CenterHow Seal fits GxP

Questions about Seal.

What is Seal?

Seal makes every GxP run better than the last. Lab, manufacturing and quality work runs on Seal, where Neil, your AI agent, learns from every run and configures the next improvement for you to approve.

Why Seal over a standalone LIMS, QMS or MES?

Lab, manufacturing and quality run on one platform, so a result, its batch and its investigation are linked rather than reconciled across systems, and Neil can work across all of them. Start with one workflow and add the next when you are ready.

How are changes validated?

Each change carries its specifications, test evidence and required approvals, so a validated process can keep improving instead of freezing. Your team verifies each change before release, and earlier runs keep the version they used.

Can Neil change a live process?

Neil proposes changes. Your team tests and approves them before they go live. Neil works within your permissions; you can disable AI across the organisation.

Do we have to replace our existing systems?

No. Start with one process, connect the systems you keep and move more work into Seal when you’re ready.

Who uses Seal?

Paradromics, Bioventix, Acclinate, Skye Biologics and MiAlgae. Read their customer stories for measured results.

See your process in Seal.

Bring an SOP, a batch record or a problem that keeps coming back, and watch Neil configure it.

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