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LabVantage suits labs whose workflows have settled. Seal changes when your workflows change.

Seal, the GxP execution system, is your eBR, your QMS and more. Neil, your AI agent, does the paperwork across your systems. You sign. Bioventix cut document admin time by 80%. Start with one process beside LabVantage.

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Where LabVantage falls short.

From LabVantage’s own pages and its launch of CORTEX.

  • LabVantage, live
    Within months
    Seal, a first process
    48 hours

    Months to go live.

    LabVantage says that with its Professional Services team you could go live within months. Seal has a first process working for you to evaluate within 48 hours, once the scope is agreed and the inputs received.

    LabVantage, LIMS
  • The lab
    LabVantage LIMS
    MES
    Another system
    QMS
    Another system
    Between them
    Web services

    Batch and quality sit elsewhere.

    LabVantage connects its LIMS through web services to “ERP, MRP, MES, QMS, and more”. In Seal, the lab, the batch and quality are one set of records.

    LabVantage, LIMS
  • Standard SaaS
    “customization is not possible”
    Core business logic
    No changes
    Unique workflows
    Enterprise SaaS

    Customisation takes a bigger edition.

    In LabVantage’s Standard SaaS, “customization is not possible”, and unique workflows call for Enterprise SaaS. In Seal, any process can change, and each change runs its selected acceptance tests before publication.

    LabVantage, Ways to Deploy
  • LIMS courses
    12
    Certification
    A programme of its own
    A customer
    “Our lack of instruction set us back.”

    It takes courses to learn.

    LabVantage lists 12 LIMS courses and a certification programme. A customer on its training page says: “Our lack of instruction set us back.”

    LabVantage, Training & Certification
  • CORTEX agents
    Inside the LIMS
    They help with
    Worksheets, samples, stability
    Neil
    Drafts the change

    Its AI works in the LIMS. Neil does the paperwork.

    LabVantage CORTEX, launched in March 2026, puts agents inside the core LIMS to help with worksheets, samples and stability studies. Neil prepares the change itself and the paperwork around it, for your team to approve.

    News-Medical, March 2026

See it in Seal.

Real Seal screens with fictional test data: one result outside its limit, from the sample to the investigation, then Neil’s overnight release review.

  1. 1

    Each result with its method and source.

    Release test S-041-12: every result carries its method version, instrument file and limit, and the batch it came from.

    Sample S-041-12, release testing, in Seal: linked to batch B-041 and a potency preparation, a table of results for potency, impurity A and water content with unit, limit, status, method and source, and water content outside its limit with the investigation open.
    1. The batch it came fromB-041, linked to the sample.
    2. Method and source on every rowEach result keeps its method version, instrument file and limit.
    3. The exception, at the resultWater content 0.72% against ≤ 0.50%, with the investigation open.
  2. 2

    The investigation starts with its evidence.

    INV-041 opens on the result outside its limit, with the instrument file, the method, qualification and wider impact to assess.

    Investigation INV-041, laboratory review, in Seal: water content 0.72% against a limit of 0.50% or less, linked to sample S-041-12, a table of evidence to assess for source acquisition, method execution, qualification and wider impact, and the conclusion still open.
    1. The result in questionWater content: 0.72% against a limit of ≤ 0.50%.
    2. From the sampleS-041-12, linked to the investigation.
    3. What to assessThe instrument file, the method, qualification and wider impact.
  3. 3

    Neil checks every lot. People decide.

    Overnight, Neil checked each lot against its release plan and said what its record leaves out.

    The release board in Seal: 111 lots in release across three sites, $123M waiting, 86 with nothing open, and a table of the lots with findings, each with Neil’s summary, its value and a predicted certification date.
    1. The morning, in two lines111 lots and $123M waiting. 86 need only a decision.
    2. Neil’s summary of each lotWhat is open, and where Neil found it.
    3. A predicted certification dateFrom how long this site’s lots have taken.

What Seal’s customers measured.

Each figure links to the customer’s story.

QualityAcclinate and Skye Biologics

−50%
quality cycle times at Acclinate, from a procedure change to everyone trained.Acclinate
−40%
non-conformances at Skye Biologics, with training checked before execution.Skye Biologics

RecordsMiAlgae and Bioventix

−75%
documentation time at MiAlgae, from the lab to commercial production.MiAlgae
−80%
document admin time at Bioventix, after two decades on paper.Bioventix

LabVantage and Seal, side by side.

Every source is listed under References.

LabVantageSeal
What it isLIMS-based informatics platform¹The GxP execution system, with LIMS built in
Built forLaboratories in many industries²Process development, the lab, manufacturing, batch release and quality
Data modelThe sample, its data sets and specifications³⁴Primitives your team composes: record types, their relationships, steps and checks
AICORTEX agents in the LIMS: worksheets, samples, stability⁵Neil, Seal’s AI agent, prepares changes to the process; your team approves them
On the platformLIMS, ELN, LES, SDMS, analytics¹LIMS, ELN, SDMS, batch records, QMS
MES and QMSOther systems, through web services²The same platform and records
Changing core logicEnterprise SaaS or on-premises only⁶Your process, with selected tests on each change
Configuring itDrag-and-drop tools, courses, a 600-strong services team⁷⁸⁹Your team, with Neil preparing it from your procedures
A result’s identityParameter list, dataset, replicate³Sample, method and spec version
Getting startedPre-configured industry LIMS, live “within months”¹²A 48-hour evaluation of one process, once the scope is agreed and the inputs received

Summary

The story
LabVantage is good for testing laboratories whose workflows are settled. Its chief executive describes its LIMS as “nearly four decades of innovation”; by 2007 it was sold as Sapphire, a thin-client LIMS, and in 2009 LabVantage bought Life Technologies’ SQL*LIMS business.¹⁰¹¹¹² A result is still a data item entered against “SDIs (typically Samples)”, with versioned specifications attached to the sample.³⁴ LabVantage says its architecture, on common programming languages, needs “no proprietary language or special training”,² and it also runs courses in administration, Web Page Designer and workflow administration, and a services team “600-strong” to implement, validate and manage the platform.⁸⁹ Its AI, LabVantage CORTEX, launched in March 2026, puts agents “inside the core LIMS” to help with worksheets, samples and stability studies.⁵ If your workflows are typical and your processes straightforward, its Standard SaaS can work well.⁶ That is rare, and rarer now that the work changes so fast.

1What LabVantage offers.

LabVantage sells laboratory informatics: its LIMS, with ELN, LES, SDMS and analytics in one architecture and licensing model.¹ It serves laboratories from pharma and biobanking to oil and gas and forensics.² It is configured in the browser with drag-and-drop tools,⁷ and its pharma edition comes “pre-configured with pharma and biotech templates and workflows”, which LabVantage says saves “up to 85% in implementation costs”.¹³

2Neil does the paperwork across LabVantage. You sign.

You can keep LabVantage. Seal’s LabVantage connection reads approved REST web services and does not write to the LIMS. Once selected records are shared, Neil, your AI agent, can list the results read for a sample by data set and replicate and flag any value whose source identity is incomplete, so a remeasurement stays apart from the original. Your team reviews what it prepares. Neil is not used in GMP execution.

3Start beside LabVantage.

  1. Choose one stability study, release test or incoming-inspection workflow, ideally one where results must reach batch review or a quality decision.
  2. Bring the protocol or method, a redacted specification, the results recorded so far and an instrument export. Start with sample material, or arrange an NDA first.
  3. Neil proposes the workflow from your approved documents, and your team checks the interpretation against the source. Once the scope is agreed and the inputs received, Seal prepares the first working process and its validation pack to evaluate within 48 hours. Production timing then depends on scope, interfaces, migration and your release requirements.
  4. Connect LabVantage read-only for the samples and data items the workflow needs, matched on their full identity.
  5. Agree which system owns each record during the transition. Work outside the scope stays in LabVantage.

References

  1. 1Laboratory Informatics and Scientific Data Advisory, LabVantage Solutions. https://www.labvantage.com/ (read 5 November 2026)
  2. 2LIMS: Laboratory Information Management System, LabVantage Solutions. https://www.labvantage.com/informatics/lims/ (read 5 November 2026)
  3. 3EnterDataItem action reference, LabVantage documentation. https://vantagecare.labvantage.com/labvantagedoc/Content/actions/sapphire/action/EnterDataItem.html (read 5 November 2026)
  4. 4AddSDISpec action reference, LabVantage documentation. https://vantagecare.labvantage.com/labvantagedoc/Content/actions/sapphire/action/AddSDISpec.html (read 5 November 2026)
  5. 5LabVantage Solutions introduces LabVantage CORTEX, advancing its LIMS platform for AI-driven laboratory operations, News-Medical, 10 March 2026. https://www.news-medical.net/news/20260310/LabVantage-Solutions-introduces-LabVantage-CORTEX-advancing-its-LIMS-platform-for-AI-driven-laboratory-operations.aspx (read 5 November 2026)
  6. 6LIMS Deployment: SaaS or On-Premises, LabVantage Solutions. https://www.labvantage.com/informatics/ways-to-deploy/ (read 5 November 2026)
  7. 7Laboratory Software: Technology, LabVantage Solutions. https://www.labvantage.com/informatics/technology/ (read 5 November 2026)
  8. 8LIMS Training: In-Person or Online, LabVantage Solutions. https://www.labvantage.com/services/customer-success/training/ (read 5 November 2026)
  9. 9LIMS Services, LabVantage Solutions. https://www.labvantage.com/services/ (read 5 November 2026)
  10. 10LIMS software company offering AI-powered advanced analytics (Who We Are), LabVantage Solutions. https://www.labvantage.com/who-we-are/ (read 5 November 2026)
  11. 11Sapphire, Scientific Computing World, 23 January 2007. https://www.scientific-computing.com/press-releases/sapphire (read 5 November 2026)
  12. 12LabVantage acquires SQL*LIMS business, Scientific Computing World, 1 September 2009. https://www.scientific-computing.com/analysis-opinion/labvantage-acquires-sqllims-business (read 5 November 2026)
  13. 13The only pre-validated, pre-configured LIMS for Pharma and Biotech, LabVantage Solutions. https://www.labvantage.com/industries/pharma-biotech/ (read 5 November 2026)

AQuestions and answers

Is Seal better than LabVantage?

Yes. LabVantage is good for testing laboratories whose workflows are settled. Its chief executive describes its LIMS as “nearly four decades of innovation”; by 2007 it was sold as Sapphire, a thin-client LIMS, and in 2009 LabVantage bought Life Technologies’ SQL*LIMS business. A result is still a data item entered against “SDIs (typically Samples)”, with versioned specifications attached to the sample. LabVantage says its architecture, on common programming languages, needs “no proprietary language or special training”, and it also runs courses in administration, Web Page Designer and workflow administration, and a services team “600-strong” to implement, validate and manage the platform. Its AI, LabVantage CORTEX, launched in March 2026, puts agents “inside the core LIMS” to help with worksheets, samples and stability studies. If your workflows are typical and your processes straightforward, its Standard SaaS can work well. That is rare, and rarer now that the work changes so fast. Seal has no fixed model of one kind of work. It is built from primitives: record types, the relationships between them, and the steps and checks that use them, which your own team composes into your process, with Neil able to prepare each change for approval. So one platform runs process development, the laboratory, manufacturing, batch release and the quality system, and each change becomes a new version, released once its selected tests pass, while earlier runs keep theirs. Moving from paper, Bioventix put its quality system and lab records on Seal and cut document admin time by 80%.

Is Seal a LIMS?

Yes. Seal covers sample management, specifications, analytical methods, stability, environmental monitoring and microbiology, OOS and OOT investigations, reference standards, instrument data and certificates of analysis, on the same records as batch records and the quality system.

Do we have to replace LabVantage?

No. Seal’s LabVantage connection issues read-only requests to approved REST web services, so LabVantage stays in place while you start one workflow in Seal. SOAP services need an approved gateway.

Does LabVantage run batch records or a quality system?

Its product list runs from LIMS, ELN, LES and SDMS to R&D data, analytics and AI, with no batch record or QMS product, and it connects through web services to MES and QMS products. In Seal, batch records and the quality system run on the same records as the laboratory.

How does LabVantage’s AI compare with Neil?

LabVantage launched CORTEX in March 2026, whose agents work inside the core LIMS, helping with worksheets, sample management and stability studies. It describes the agents it shows as concepts being developed. Give Neil an approved specification, method or protocol and it proposes the configuration as a controlled change for your team to check and approve. Neil is not used in GMP execution.

How long does it take to start with Seal?

Once the scope is agreed and the inputs received, Seal prepares a first working process and its validation pack to evaluate within 48 hours, configured from one of your methods, protocols or procedures. Production timing then depends on scope, interfaces, migration and your release requirements.

Start beside LabVantage.

Keep LabVantage. Seal’s LabVantage connection reads approved REST web services read-only, so Neil can work from them while you start one stability study or release test, and nothing has to move on day one.

Book a demo