# Seal

> Seal makes every GxP run better than the last. Lab, manufacturing and quality work runs on Seal, where Neil, your AI agent, learns from every run and configures the next improvement for you to approve. Neil works across your records and connected systems to analyse data, configure processes and propose improvements from run evidence. Your team tests and approves process changes before release.

## How Seal evolves with AI

Each improvement can become a new process version with its specifications, test evidence and approvals attached. Earlier runs retain the version they used, so the system can evolve without rewriting its history. Every run adds context for the next investigation or improvement.

Lab, manufacturing and quality workflows use a shared ontology in Seal. It defines the types of records used in the work and their relationships: a sample belongs to a batch, a result comes from a test, and an investigation links to the affected work. Teams and Neil can follow those relationships to the evidence behind a decision. Each record retains its history, and earlier runs keep the process version they used.

## What Neil does

- Answers questions across permitted records and connected systems, with the sources shown.
- Investigates results, bringing development, manufacturing and quality evidence together.
- Turns a procedure into a proposed working process in Seal, for your team to test and approve.
- Proposes improvements from the evidence of real runs. Neil proposes; people approve. It never releases a change on its own, and AI features can be switched off for the whole organisation.
- Customer data is not used to train AI models under Seal’s agreements.
- In line with the EU’s draft GMP Annex 22 on AI (consultation version, July 2025, not yet adopted): Neil is not used in GMP execution. It helps set up configuration, which your team verifies and releases under change control, and prepares evidence for qualified people to assess. Detail: https://seal.run/regulatory/guide#answer-2.11

## Products and key pages

- [Platform](https://seal.run/platform): lab, manufacturing and quality workflows on a shared ontology, with continuous validation.
- [Neil](https://seal.run/neil): Seal’s AI agent for GxP work, and the jobs it prepares.
- [Blueprints](https://seal.run/blueprints): starting processes for LIMS, ELN, MES and electronic batch records, QMS and eQMS, document control, training and more.
- [Regulatory and validation](https://seal.run/regulatory): continuous validation, computer system validation (CSV/CSA), GAMP 5 Second Edition, 21 CFR Part 11, EU Annex 11, the EU’s draft Annex 22 on AI and AI data controls.
- [Integrations](https://seal.run/integrations): the systems and instruments Seal connects to, and what each connection can read or write.
- [Compare](https://seal.run/compare): how Seal compares with the eQMS, LIMS, ELN, MES, validation, document, maintenance and scientific data systems life sciences teams run today, what each leaves out, and how to switch to Seal.
- [Instruments](https://seal.run/instruments): Seal works with any instrument whose software saves a file. The [instrument catalogue](https://seal.run/instruments/catalogue.txt) lists the models laboratories connect, by manufacturer.
- [Customers](https://seal.run/impact): published customer stories.

## Published customer results

- [Paradromics](https://seal.run/impact/paradromics): Paradromics cuts operator paperwork by 80%. (Operator paperwork: −80%; Traveler review time for engineers: −90%; Process innovation time: −15%)
- [Bioventix](https://seal.run/impact/bioventix): Bioventix cuts document admin time by 80%. (Document admin time: −80%; Audit readiness: Customer-approved; Data traceability: 100%)
- [Acclinate](https://seal.run/impact/acclinate): Acclinate cuts quality cycle times by 50%. (Quality cycle times: −50%; Time taken to prepare for audits: −40%; Confidence in correct training: 100%)
- [Skye Biologics](https://seal.run/impact/skye-biologics): Skye Biologics increases production throughput by 35%. (Increase in throughput: +35%; Non-conformances: −40%; Procedure review cycles: 2× faster)
- [MiAlgae](https://seal.run/impact/mialgae): MiAlgae cuts documentation time by 75%. (Documentation time: −75%; Traceability: Instant lot genealogy; Scale: Lab to commercial on one platform)

## Contact

- Book a demo: https://seal.run/start
- Contact: https://seal.run/contact or contact@seal.run
- Offices: London Bridge, UK; Menlo Park, CA; Research Triangle Park, NC
- Company: Opvia Ltd., trading as Seal